硫辛酸对黄羽肉鸡生长性能、抗氧化能力和免疫功能的影响

本试验旨在研究饲粮中添加硫辛酸对黄羽肉鸡生长性能、抗氧化能力和免疫功能的影响。将 ６０只 ２１日龄体重相近的黄羽肉鸡随机分为 ２组，即对照组和硫辛酸组，每组 ５个重复，每个重复 ６只鸡。对照组饲喂基础饲粮，硫辛酸组饲喂在基础饲粮中添加 ３００ｍｇ／ｋｇ硫辛酸的试验饲粮，试验期 ３０ｄ。结果表明，硫辛酸对黄羽肉鸡的生长性能无显著影响（Ｐ＞０．０５）；在试验第 １５天时，硫辛酸可以显著提高黄羽肉鸡血清总超氧化物歧化酶活性（Ｐ＜０．０５）、降低一氧化氮含量（Ｐ＜０．０５），促进脾脏的发育（Ｐ＜０．０５），提高血清免疫球蛋白 Ｇ含量（Ｐ＜０．０１）；在试验第 ３０天时，硫辛酸可以显著降低黄羽肉鸡血清丙二醛含量（Ｐ＜０．０５）、提高抑制羟自由基的能力（Ｐ＜０．０１），提高由伴刀豆球蛋白 Ａ和脂多糖刺激的外周血淋巴细胞转化率以及血清免疫球蛋白 Ｇ含量（Ｐ＜０．０５）。由本试验可知，饲粮中添加 ３００ｍｇ／ｋｇ硫辛酸可以在一定程度上提高肉鸡抗氧化能力，增强其免疫功能。

Lipoic Acid: Effects on Growth Performance,Antioxidant Capacity and Immune Function in Yellow-Feathered Broilers

The study was conducted to investigate the effects of lipoic acid on growth performance,antioxidant capacity and immune function in yellow-feathered broilers.Sixty 21-day-old yellow-feathered broiler chickens with the similar body weight were randomly divided into control group and lipoic acid group,and there were 5 replicates per group and 6 broilers per replicate.The control group was fed a basal diet,and the lipoic acid group was fed the basal diet supplemented with 300 mg/kg lipoic acid.The experiment period was 30 days.The results showed that lipoic acid supplementation in the diet did not significantly affect growth performance(P>0.05),but promoted the development of spleen(P<0.05),increased total superoxide dismutase activity(P<0.05) and immunoglobulin G content(P<0.01),and decreased nitric oxide content(P<0.05) in serum of broilers on the 15th day of the experiment;lipoic acid supplementation in the diet decreased serum malondialdehyde content(P<0.05),and increased the capacity of scavenging ·OH(P<0.01) and immunoglobulin G content(P<0.05) in serum and the lymphocyte transformation rate stimulated by concanavalin A and lipopolysaccharide in peripheral blood(P<0.05) of broilers on the 30th day of the experiment.In conclusion,the supplementation of lipoic acid in the diet can enhance antioxidant capacity and immune function in broilers.