| 亚硒酸钠对小鼠免疫器官组织结构的影响 |
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| 引用本文： | 郑素玲,郑素琴,石洪陵,柴凤瑞.亚硒酸钠对小鼠免疫器官组织结构的影响[J].动物医学进展,2004,25(4):94-96. |
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| 作者姓名： | 郑素玲 郑素琴 石洪陵 柴凤瑞 |
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| 作者单位： | 唐山师范学院生物系,河北,唐山,063000;华北煤炭医学院病理教研室,河北,唐山 |
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| 摘 要： | 为了研究亚硒酸钠对小鼠胸腺、脾脏组织结构的影响。给小鼠腹腔内注射 0 .5%半乳糖(50 mg/ kg/ d) ,连续 8周 ,建立衰老模型组 ;自第 4周开始给衰老用药组腹腔注射亚硒酸钠(2 mg/ kg/ d) ,连续 4周。应用电子天平称量小鼠脾、胸腺重量 ,并对胸腺、脾进行常规石蜡切片 ,观察衰老模型组、衰老用药组和对照组之间胸腺、脾组织结构的差异。结果表明 ,硒对老龄小鼠胸腺、脾的重量影响不大 ,组织切片观察显示 ,亚硒酸钠有延缓小鼠脾脏、胸腺组织衰老的作用 ,故亚硒酸钠对延缓小鼠免疫器官衰老有一定的作用
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| 关 键 词： | 亚硒酸钠 胸腺 脾 组织切片 免疫器官 |
| 文章编号： | 1007-5038(2004)04-0094-03 |
| 修稿时间： | 2004年1月15日 |
The Effects on Sodium Selenite on the Structure of Immune Organization in Rats |
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| ZHENG Su-ling,ZHENG Su-qin,SHI Hong-ling,CAI Feng-rui.The Effects on Sodium Selenite on the Structure of Immune Organization in Rats[J].Progress In Veterinary Medicine,2004,25(4):94-96. |
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| Authors: | ZHENG Su-ling ZHENG Su-qin SHI Hong-ling CAI Feng-rui |
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| Institution: | ZHENG Su-ling~1,ZHENG Su-qin~2,SHI Hong-ling~1,CAI Feng-rui~1 |
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| Abstract: | To study effects of selenium(Se) on histological structure of the immune organ in rats.Methods: Km rats were given intraabdominal injection of D-Galactose(50 mg/kg) once a day for 8 weeks. After 4 weeks a group of Km rats were given intraabdominal injection of Se(2 mg/kg) at same time. with the electronic-weighting system and the technique of histological section observed if injecting of Se made weight and structure changes on the rats' spleen and thymus. Result:The weight of the thymus and spleen were not changed.but the involution rats' thymic lobules were quite distinct. Se could delay course of senility of rats' spleen and thymus. |
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| Keywords: | selenium thymus spleen histological section immune organ |
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