Associations between canine benign and malignant neoplasms |
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Authors: | Alan P. Bender Gail Papermaster Bender C. Richard Dorn Robert Schneider |
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Affiliation: | 1. Department of Veterinary Preventive Medicine, USA;2. Department of Medicine, Ohio State University, USA;3. Department of Epidemiology and Preventive Medicine, University of California, Davis, CA 95616, U.S.A. |
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Abstract: | Associations between benign and malignant neoplasms of the dog were quantitatively evaluated. Using histologically confirmed submissions and population-based methodology, canine benign tumors were significantly associated with both the unordered and subsequent development of additional distinct malignancies in the same dogs. A detailed examination of the methods indicated that these results are not likely due to methodologic artifact. The implication is that benign and malignant tumor development are associated and that the occurence of a benign neoplasm is an indicator of a parallel predisposition to malignancy. |
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