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Equine sarcoid of the glans penis with bovine papillomavirus type 1 in a miniature horse (Falabella)
Authors:Kikumi OGIHARA  Akikazu ISHIHARA  Makoto NAGAI  Kazutaka YAMADA  Testuya MIZUTANI  Mei HARAFUJI  Hisanari NISHIO  Hiroo MADARAME
Abstract:A 23-year-old Falabella gelding kept in Tochigi, Japan, for more than 20 years presented with a recurrent mass of the glans penis that was first noticed about a year earlier. Partial phallectomy was performed with no adjunctive therapy for local regrowth of the mass. The horse was euthanized 3 months after surgery for urinary retention due to suspected regrowth. The resected mass affected the genital and urethral mucosa of the glans penis, and was diagnosed as equine sarcoid by histopathology and identification of bovine papillomavirus (BPV) DNA. Phylogenetic analysis of the BPV genome of the sarcoid showed high sequence homology to BPV type 1 (BPV-1) from Hokkaido, Japan, suggesting a geographical relationship for BPV-1 in Japan.
Keywords:bovine papillomavirus  equine sarcoid  glans penis  mucosal sarcoid  phylogenetic analysis
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