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Microbiology. Action at a distance--bacterial flagellar assembly
Authors:Macnab R M
Institution:Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA. robert.macnab@yale.edu
Abstract:The rotating motion of a helical flagellum enables a bacterium to swim toward positive stimuli and away from danger. But how is the flagellum, composed of many different proteins, assembled? In a Perspective, Macnab explains how subunits of the protein flagellin flow down a channel inside the flagellum and are then added to its tip through the action of a rotating pentameric cap complex (Yonekura et al.).
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