A 50-year record of quinolone and sulphonamide antimicrobial agents in Seine River sediments |
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| Authors: | Fatima Tamtam Barbara Le Bot Tuc Dinh Sophie Mompelat Joelle Eurin Marc Chevreuil Philippe Bonté Jean-Marie Mouchel Sophie Ayrault |
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| Institution: | 1.Laboratoire Hydrologie et Environnement, EPHE,Paris Cedex,France;2.Ecole des Hautes Etudes en Santé Publique (EHESP), Laboratoire d’Etude et de Recherche en Environnement et Santé (LERES),Rennes,France;3.Laboratoire des Sciences du Climat et de l’Environnement (LSCE) UMR CNRS/CEA/UVSQ 1572—IPSL,Gif-sur-Yvette Cedex,France;4.UMR Sisyphe 7619,Paris Cedex,France |
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| Abstract: | Purpose Even though sediments may represent a reservoir for antimicrobial agents, little is known about the persistence of these molecules
over time or their accumulation. In this study, six antimicrobial agents, oxolinic acid, flumequine, nalidixic acid, norfloxacin,
sulphamethoxazole and trimethoprim, were investigated in a sediment core from the Seine River. This work aimed to (1) measure
antimicrobial agent contamination levels in the sediment and identify their origins, (2) obtain information on the persistence
of these compounds in sediment over long periods (>4 years) and (3) show the existence of a historical record in sediment
of river contamination by antimicrobial agents. |
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