| 乳化复合液体维生素制备工艺的初步研究 |
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| 引用本文： | 栾明娜,周玉武,徐福亮,陈大健. 乳化复合液体维生素制备工艺的初步研究[J]. 青海畜牧兽医杂志, 2010, 40(2): 24-25 |
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| 作者姓名： | 栾明娜 周玉武 徐福亮 陈大健 |
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| 作者单位： | 1. 青岛康地恩药业有限公司,青岛,266111
2. 江苏省滨海县动物卫生监督所,盐城,224500 |
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| 摘 要： | 对维生素口服溶液剂制备工艺条件进行了筛选,并对所用乳化剂种类,助乳化剂用量和乳化温度进行考察。结果表明：对处方量的维生素采用12．5％的乳化剂OP-10,5％的稳定剂,乳化温度60℃,所制备的液体多维在4～25℃下12个月内无沉淀析出,外观颜色无明显改变,表明本制剂所制定的工艺路线可行,适合大批量生产。
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| 关 键 词： | 液体维生素 微乳 制备工艺 |
Study on preparation procedure for Compound Vitamins Solution |
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| LUAN Ming-na et al. Study on preparation procedure for Compound Vitamins Solution[J]. Chinese Qinghai Journal of Animal and Veterinary Sciences, 2010, 40(2): 24-25 |
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| Authors: | LUAN Ming-na et al |
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| Affiliation: | LUAN Ming-na et al(Qingdao KDN Pharmaceutical Co.Ltd,Qingdao,266111) |
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| Abstract: | To optimize the preparation procedure for compound vitamins micro -emulsion. Affecting Factors including species of emulsifier,quantity of stabilizer and emulsifying temperature were studied. The results showed that the optimization conditions were ：the concentration of emulsifier OP - 10 was 12.5%, the concentration of stabilizer was 5 %, and the emulsifying temperature was 60℃. In this condition, the preparation was stable at 4 - 25℃ for 1 year. There was no significant change in color and appearance, indicating that this method can be adopted for mass production. |
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| Keywords: | Liquid vitamin Micro-emulsion Preparation procedure |
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