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Antifeedant activity of some diterpenoids
Affiliation:1. Acute Critical Illness Center,Jinshan Hospital, Fudan University, 1508 Longhang Road, Shanghai 201508, China;2. Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China;3. Department of Pharmacy, Shanghai First Maternity and Infant Hospital, Tongji University School of medicine, Shanghai 201204, China;1. INTEQUI-CONICET, Universidad Nacional de San Luis, Área de Química Orgánica, Almirante Brown 1455, D5700HGC San Luis, Argentina;2. Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, Chacabuco 915, 5700 San Luis, Argentina;3. Instituto Multidisciplinario de Investigaciones Biológicas (IMIBIO-CONICET), Chacabuco 915, 5700 San Luis, Argentina
Abstract:The antifeedant activity of six diterpenes against the fourth instar nymphs and adults of Henosepilachna vigntioctopunctata was evaluated using a dual choice leaf disc bioassay. Caryoptin was the most effective antifeedant among the compounds tested. Andrographolide, wightionolide and 3-epicaryoptin did not deter feeding by adults. The possible relationship of structure to antifeedant activity is discussed.
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