A new flavan from Elephantorrhiza goetzei |
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| Institution: | 1. Department of Chemistry, University of Botswana, Private Bag 0022, Gaborone, Botswana;2. Department of Biological Sciences, University of Botswana, Private Bag 0022, Gaborone, Botswana;1. Department of Pharmacology, School of Pharmacy, College of Health Sciences, Mekelle University, Mekelle, Ethiopia;2. Department of Pharmacognosy, School of Pharmacy, College of Health Sciences, Mekelle University, Mekelle, Ethiopia;1. Wageningen University & Research, Department of Animal Sciences, Animal Nutrition Group, PO Box 338, 6700 AH Wageningen, the Netherlands;2. Department of Animal, Rangeland and Wildlife Sciences, Mekelle University, PO Box 231, Mekelle, Ethiopia;3. UMR 1225 IHAP INRA/ENVT, 23 Chemin des Capelles, F-31076 Toulouse, France;4. Université de Toulouse, INP-ENVT, 23 Chemin des Capelles, F-31076 Toulouse, France;5. Laboratory of Organic Chemistry and Chemical Biology, Department of Chemistry, University of Turku, FI-20014 Turku, Finland;6. Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, PO Box 80163, 3508 TD Utrecht, the Netherlands;1. Soil Science Discipline, School of Agricultural, Earth and Environmental Sciences, University of KwaZulu-Natal, Private Bag X01, Scottsville, 3209, South Africa;2. Faculty of Agriculture, Women’s University in Africa, P. O. Box MP1222, Mt. Pleasant, Harare, Zimbabwe;3. Department of Soil Science and Agricultural Engineering, University of Zimbabwe, P.O. Box MP167, Mt. Pleasant, Harare, Zimbabwe;1. Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar 608002, Tamilnadu, India;2. Postgraduate and Research Department of Biochemistry, Adhiparasakthi College of Arts and Science, G.B. Nagar, Kalavai, Vellore District 632506, Tamil Nadu, India;3. Department of Animal and Food Bioscience, College of Natural Science, Konkuk University, Danwoldong, Chungju, South Korea;1. School of CEE, Nanyang Technological University, Singapore;2. Department of CEE, National University of Singapore, Singapore |
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| Abstract: | A new compound, 3,3′,4′,5,6,7,8-heptahydroxyflavan (1), was isolated from the roots of Elephantorrhiza goetzei. The crude extract, and its n-butanol and residual water fractions showed antimicrobial activity. Semi-purified extracts showed higher activity and of the purified compounds only methyl gallate gave activity below 100 μg of sample. |
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