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老瓜头内生真菌LGT-LA代谢产物研究
引用本文:李娜,吴秀丽,陈靖,段海婧,秦路平,刘成. 老瓜头内生真菌LGT-LA代谢产物研究[J]. 安徽农业科学, 2012, 40(3): 1417-1418
作者姓名:李娜  吴秀丽  陈靖  段海婧  秦路平  刘成
作者单位:宁夏医科大学药学院,宁夏回药现代化工程技术研究中心,宁夏银川750004;宁夏医科大学药学院,宁夏回药现代化工程技术研究中心,宁夏银川750004;第二军医大学药学院,上海200433;第二军医大学药学院,上海,200433;宁夏医科大学科技中心,宁夏银川,750004
基金项目:国家自然科学基金,宁夏自治区科技攻关项目
摘    要:[目的]为科学利用老瓜头及其内生真菌提供参考。[方法]采用多种色谱分离技术,对老瓜头内生真菌LGT-L4发酵物乙酸乙酯萃取部分进行分离纯化,并通过核磁共振(NMR)、质谱等波谱方法对分离得到的化合物进行结构鉴定。[结果]从老瓜头内生真菌LGT-L4发酵物乙酸乙酯萃取部分分离得到5个化合物,分别为对羟基苯甲醛、尿嘧啶苷、L-焦谷氨酸、甲基焦谷氨酸和蔗糖。[结论]明确了老瓜头内生真菌LGT-L4代谢产物。

关 键 词:老瓜头  内生真菌  化学成分  发酵

Study on the Chemical Constituents of Endophytic Fungus LGT-L4 from Cynanchum komarovii
Affiliation:LI Na et al (School of Pharmacy,Ningxia Medical University,Ningxia Research Center of Modern Hui Medicine Engineering and Technology,Yinchuan,Ningxia 750004)
Abstract:[Objective] The aim was to provide references for using C.komarovii and its endophytic fungus scientifically.[Methods] Constituents were isolated from ethyl acetate portion of endophytic fungus LGT-L4 leavening from C.komarovii by modern chromatographic techniques and their structures were determined by physic-chemical evidences and spectroscopic methods such as NMR and mass spectra.[Results] Five known chemical constituents were isolated from ethyl acetate portion of endophytic fungus LGT-L4 leavening from C.komarovii,identified as parahydroxybenzaldehyde,uridine,L-focal glutamic acid,focal glutamic acid methyl and sucrose.[Conclusion] The metabolites of endophytic fungus LGT-L4 from C.komarovii were defined.
Keywords:Cynanchum komarovii Al.Iljinski  Endophytic fungus  Chemical constituents  Fermentation
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