|
|||||
|
|
Seroincidence of porcine T. solium infection in the Peruvian highlands |
|
| Authors: | Garcia H H,Gonzalez A E,Gavidia C,Falcon N,Bernal T,Verastegui M,Rodriguez S,Tsang V C W,Gilman R H Cysticercosis Working Group in Peru |
| Affiliation: | a Departments of Microbiology and Pathology, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, San Martin de Porras, Lima, Peru b Department of Transmissible Diseases, Instituto Nacional de Ciencias Neurologicas, Jr. Ancash 1271, Barrios Altos, Lima, Peru c Department of International Health, Johns Hopkins Bloomberg School of Hygiene and Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA d School of Veterinary Medicine, Universidad Nacional Mayor de San Marcos, Av. Circunvalacion s/n, Salamanca de Monterrico, Lima, Peru e Asociacion Benefica PRISMA, Carlos Gonzalez 251, San Miguel, Lima, Peru f Parasitic Diseases Branch, Centers for Disease Control, 4770 Buford Highway, Mail Stop F-13, Atlanta, GA 30333, USA |
| Abstract: | We performed repeated serological sampling of pigs in an endemic area of the Peruvian highlands (eight villages) to assess the feasibility of detecting incident cases of Taenia solium infection as indicators of ongoing transmission of the parasite. A total of 2245 samples corresponding to 1548 pigs were collected in three sampling rounds (n=716, 926, and 603, respectively). Village-period specific seroprevalences of antibodies by enzyme-linked immunoelectrotransfer blot (EITB) assay varied from 39% (95% CI: 34, 44) to 76% (95% CI: 72, 79). The prevalence of cysticercosis increased with the age of the pigs (similarly for both sexes). Around 40% of pigs were re-sampled at the end of each 4-month period. Crude incidence risks were 48% (57/120, 95% CI: 43–52) and 58% (111/192, 95% CI: 54–61) for each period. A proportion of seropositive animals became seronegative at the end of each period (23 and 15%). Incidence varied by the village, and the exposure period, and was higher in males than females (but did not differ by age). |
| Keywords: | Cysticercosis Taenia solium EITB Epidemiology Incidence Longitudinal studies |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |