| 挤出-滚圆法制备味连须微丸 |
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| 引用本文： | 张德周,周晓燕,陈超,刘汉儒. 挤出-滚圆法制备味连须微丸[J]. 中兽医医药杂志, 2013, 32(2): 9-11 |
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| 作者姓名： | 张德周 周晓燕 陈超 刘汉儒 |
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| 作者单位： | 西南大学药学院,重庆,400716 |
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| 基金项目： | 石柱黄连规范化种植基地及其SOP优化升级研究(2011BAI13B02-1) |
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| 摘 要： | 目的：考察味连须微丸的制备工艺。方法：利用挤出-滚圆法制备微丸,采用单因素考察和正交设计筛选最优处方及工艺。结果：所得微丸的制备工艺简单,大小均匀,载药量大而均匀,适于工业化生产。
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| 关 键 词： | 味连须 微丸 制备工艺 挤出滚圆法 |
Preparation of Fibrous Root Coptidis pellets by extrusion-spheronization method |
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| ZHANG De-zhou , ZHOU Xiao-yan , CHEN Chao , LIU Han-ru. Preparation of Fibrous Root Coptidis pellets by extrusion-spheronization method[J]. Journal of Traditional Chinese Veterinary Medicine, 2013, 32(2): 9-11 |
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| Authors: | ZHANG De-zhou ZHOU Xiao-yan CHEN Chao LIU Han-ru |
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| Affiliation: | (College of Pharmaceutical Sciences,Southwest University,Chongqing 400716,China) |
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| Abstract: | Objective： To optimize the preparation technique of Fibrous Root Coptidis pellets.Methods： The pellets were prepared by extrusion-spheronization method based on the studies of influential factors,and optimal formulation was obtained by orthogonal design.Results：Prepared pellets have such advantages as simple technique,uniformity in diameters,high drug content and useful for large-scale production. |
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| Keywords: | Fibrous Root Coptidis pellets preparation technology extrusion-spheronization method |
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