增加前肢主动运动对去势大鼠桡,尺骨骨量的影响

目的：建立雄性大鼠前肢主动运动模型并观察其对去势雄性大鼠尺、桡骨骨量减少的影响。方法：建立前肢主动运动取食动物模型并云势以观察尺骨、桡骨部位骨量的影响。６月龄大鼠按体重随机分为５组。（１）对照组；（２）假手术组＋正常高度笼；（３）双侧睾丸切除组＋正常高度笼；（４）假手术组＋模型组；（５）双侧睾丸切除组＋模型组。结果：模型组大鼠的尺桡骨骨皮质都有显著增加。结论：大鼠前脚趾掌主动运动对远端尺骨和远端桡

Effect of making orchidectomized rats rise in bipedal stance on the bone mass in distal ulna and radius

Objective:To establish a raised cage model to make rats rose in bipedal stance for feeding,and observe the effect on the bone mass in distal ulna and radius of orchidectomized rats Methods:Six month old male SD rats were divided randomly into five body weight match groups:(1)control;(2)sham orchidectomized and housed in normal height cage;(3)bilaterally orchidectomized and housed in normal height cage;(4)sham orchidectomized and housed in the raised cage;(5)bilaterally orchidectomized and housed in the raised cage After twelve weeks,labeled cross sections of the distal ulna and radius were used for bone histomorphometric analysis Results:There was a significant increase in bone mass in cortical area of the ulna and radius in the raised cage model Conclusion:Making rats rise in bipedal stance could increase the bone mass in the distal ulna and radius,and prevent bone loss in these areas in the orchidectomized rats