Influence of various phosphopeptides of caseins on iron absorption |
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Authors: | Bouhallab Saíd Cinga Vladas Aít-Oukhatar Nabil Bureau François Neuville Dominique Arhan Pierre Maubois Jean-Louis Bouglé Dominique |
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Institution: | Laboratoire de Recherches de Technologie Laitière, INRA, 65 rue de Saint Brieuc, F-35042 Rennes Cedex, France. |
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Abstract: | The influence of the origin and kind of caseinophosphopeptide (CPP) on iron absorption was assessed by comparing a commercially available CPP mixture (CPPs) and derived chromatographic fractions with the purified, chemically phosphopeptide of beta-casein beta-CN(1-25)] using a perfused rat duodenal loop system; gluconate iron was used as control. Only iron complexed to beta-CN(1-25) displayed a better bioavailability than gluconate iron. The results obtained with various chromatographic fractions indicated that phosphopeptides of different origins (alpha(s)- versus beta-caseins) display specific effects. These findings contribute to the explanation of the discrepancy about the role of caseinophosphopeptides on mineral bioavailability in vivo. |
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