| 百草枯与肾上腺皮质激素对大鼠胎儿动脉管收缩的影响 |
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| 引用本文： | 沈明浩,任大勇,陈萍,李大军,权伍荣. 百草枯与肾上腺皮质激素对大鼠胎儿动脉管收缩的影响[J]. 吉林农业大学学报, 2006, 28(3): 334-337 |
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| 作者姓名： | 沈明浩 任大勇 陈萍 李大军 权伍荣 |
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| 作者单位： | 吉林农业大学食品工程学院,长春,130118;延边大学农学院,龙井,133400 |
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| 摘 要： | 试验研究了百草枯与肾上腺皮质激素对大鼠胎儿动脉管收缩的影响。结果表明:百草枯对大鼠胎儿动脉管具有明显的收缩作用,试验组与对照组比较差异显著(P<0.05);肾上腺皮质激素对大鼠胎儿动脉管具有明显的收缩作用,试验组与对照组比较差异显著(P<0.05);百草枯和肾上腺皮质激素引起收缩的临界期均为胎龄19~20 d;百草枯促进妊娠末期母鼠分泌大量肾上腺皮质激素。这说明百草枯和肾上腺皮质激素可影响大鼠胎儿动脉管的收缩。
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| 关 键 词： | 百草枯 大鼠 动脉管 肾上腺皮质激素 胚胎毒性 |
| 文章编号： | 1000-5684（2006）03-0334-04 |
| 收稿时间： | 2005-11-20 |
| 修稿时间： | 2005-11-202006-03-25 |
Effects of Paraquat and Adrenocortical Hormone on Ductus Arteriosus of Rat Fetus |
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| SHEN Ming-hao,REN Da-yong,CHEN Ping,LI Da-jun,QUAN Wu-rong. Effects of Paraquat and Adrenocortical Hormone on Ductus Arteriosus of Rat Fetus[J]. Journal of Jilin Agricultural University, 2006, 28(3): 334-337 |
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| Authors: | SHEN Ming-hao REN Da-yong CHEN Ping LI Da-jun QUAN Wu-rong |
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| Affiliation: | 1. College of Food Engineering, Jilin Agricultural University, Changchun 130118, China; 2. College of Agronomy, Yanbian University, Longjing 133400, China |
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| Abstract: | The toxic effects of paraquat and adrenocortical hormone on ductus arteriosus of rat fetus were studied.The results showed that paraquat had effects on the internal diameter of ductus arteriosus of fetuses compared with control group(P<0.05);adrenocortical hormone had effects on the internal diameter of ductus arteriosus of fetuses compared with control group(P<0.05);the critical contraction time of fetus ductus arteriosus was between day 19 and day 20.Paraquat could increase Wistar rats dams to secret adrenocortical hormone at the end of gestation.The research indicated that paraquat and adrenocortical hormone could affect ductus arteriosus of rat fetus. |
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| Keywords: | paraquat rat ductus arteriosus adrenocortical hormone embryonic toxicity |
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