Experimental assessment of the pathogenicity of H5N1 influenza A viruses isolated in Japan |
| |
| Authors: | Mase Masaji Imada Tadao Nakamura Kikuyasu Tanimura Nobuhiko Imai Kunitoshi Tsukamoto Kenji Yamaguchi Shigeo |
| |
| Institution: | Department of Infectious Diseases, National Institute of Animal Health, 3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan. |
| |
| Abstract: | We examined the pathogenicity for chickens of two H5N1 avian influenza viruses isolated in Japan, A/chicken/ Yamaguchi/7/2004 (Ck/Yamaguchi/7/04) isolated from outbreaks in commercial layer chickens, and A/duck/Yokohama/aq10/ 2003 (Dk/Yokohama/aq10/03) isolated from duck meat imported from China. All chickens inoculated intranasally with either strain died, and the viruses were reisolated from all organs examined. However, both the mean time of onset of clinical signs and the mean death time of Ck/Yamaguchi/7/04 were shorter than those of Dk/Yokohama/aq10/03. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
