Na2CO3催化微波合成乙酰水杨酸的研究 |
| |
引用本文: | 郝红英,侯巧芝,周芳,张莎莎. Na2CO3催化微波合成乙酰水杨酸的研究[J]. 安徽农业科学, 2013, 0(28): 11251-11252 |
| |
作者姓名: | 郝红英 侯巧芝 周芳 张莎莎 |
| |
作者单位: | 黄河科技学院医学院,河南郑州,450063;黄河科技学院医学院,河南郑州,450063;黄河科技学院医学院,河南郑州,450063;黄河科技学院医学院,河南郑州,450063 |
| |
基金项目: | 黄河科技学院校级科研项目(KYZR20139). |
| |
摘 要: | [目的]以水杨酸和乙酸酐为原料,采用碳酸钠作催化剂微波辐射合成乙酰水杨酸。[方法]采用正交试验法,考察了催化剂用量、微波功率、辐射时间对反应产率的影响。[结果]优选出的较佳反应条件为:取6.3 g水杨酸和9 ml乙酸酐,催化剂碳酸钠用量0.4g,微波功率400 W,辐射时间90 s。在此条件下,乙酰水杨酸产率达83.25%。[结论]采用碳酸钠微波催化合成乙酰水杨酸,反应收率较好。
|
关 键 词: | 碳酸钠 合成 乙酰水杨酸 正交试验 |
Synthesis of Acetylsalicylic Acid under Microwave Radiation Condition by Sodium Carbonate |
| |
Affiliation: | HAO Hong-ying et al (Medical School, Huanghe Science and Technology College, Zhengzhou, Henan 450063) |
| |
Abstract: | Aeetylsalicylic acid was synthesized using salicylic acid and acetic anhydride as raw materials and sodium carbonate as the catalyst. [ Method] An orthogonal experimental design was used to optimize the synthetic conditions, such as reaction sodium carbonate dos- age, the microwave power and the radiation time . [ Result ] The best optimization process was obtained as follows:salicylic acid 6.3 g, acetic anhydride 9ml,sodium carbonate dosage 0.4 g, 400 W as the microwave power, 90 s as the radiation time. Under this optimal condition, perfect yield of 83.25%could be obtained. [ Conclusion]Ideal yield of aeetylsalicylic acid was obtained by using sodium carbonate as the catalyst. |
| |
Keywords: | Sodium carbonate Synthesis Acetylsalicylie acid Orthogonal experiment |
本文献已被 CNKI 维普 万方数据 等数据库收录! |
|