新型异噁唑啉类药物合成研究进展 |
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引用本文: | 吴梦雅,武鼎铭,孙凤楠,索永波,侯林. 新型异噁唑啉类药物合成研究进展[J]. 中国兽药杂志, 2020, 54(11): 72-78 |
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作者姓名: | 吴梦雅 武鼎铭 孙凤楠 索永波 侯林 |
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作者单位: | 国家兽用药品工程技术研究中心,,,, |
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摘 要: | 异噁唑啉类药物是一种新型杀虫剂,主要用于犬和猫体外寄生虫的预防与治疗。目前已上市的异噁唑啉类药物有:Fluralaner、Sarolaner、Afoxolaner和Lotilaner。对以上四种药物的合成方法进行概述,并总结了这些合成方法的优缺点,为该类药物的工业化生产提供一定的参考依据。
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关 键 词: | 异噁唑啉类药物 寄生虫 合成 |
收稿时间: | 2020-04-23 |
修稿时间: | 2020-10-22 |
Research progress in synthesis of new isoxazolines |
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Affiliation: | National Research Center For Veterinary Medicine,Luoyang,Henan,,,, |
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Abstract: | The isoxazolines are a new type of insecticides, mainly used for the prevention and treatment of ectoparasites in dogs and cats. The isoxazolines currently in the market include: Fluralaner, Sarolaner, Afoxolaner and Lotilaner. The synthesis methods of the above four drugs are summarized, and the advantages and disadvantages of these synthesis methods are listed, which provide a certain reference basis for the industrial production of such drugs. |
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Keywords: | isoxazolines parasites synthesis |
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