Xanthone isolated from Securidaca longependunculata with activity against erectile dysfunction |
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Authors: | Rakuambo N C Meyer J J M Hussein A |
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Institution: | Department of Botany, University of Pretoria, Pretoria, South Africa. |
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Abstract: | 1,7-Dimethoxy-2-hydroxy-xanthone and 1,4-dihydroxy-7-methoxy-xanthone isolated from Securidaca longependunculata were tested for their activity on rabbit corpus cavernosum in vitro. Only the former relaxed the corpus cavernosum by 63% at 1.8 x 10(-5) mg/ml. |
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