Progress in mitochondrial nitric oxide synthase |
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Authors: | SUN Xiao-si TAN Dun-yong WANG Hua-dong YAN Liang |
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Affiliation: | Department of Pathophysiology, Medical College of Jinan University, Guangzhou 510632, China |
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Abstract: | Nitric oxide (NO) is an intra- and intercellular messenger with a broad spectrumof activities in the central nervous system, cardiovascular and immune systems. Mitochondrial nitric oxide synthase (mt-NOS), which might be a new form of NOS in mitochondria, has been discovered to be active in the regulation ofmitochondrial respiration, energy metabolism and many pathophysiological processes.In this review, the location, properties, physiological and pathophysiological significance of mtNOS were summarized. |
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Keywords: | Nitric-oxide synthase Mitochondria |
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