Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret |
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Authors: | Saki INOUE Kayoko YONEMARU Tokuma YANAI Hiroki SAKAI |
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Affiliation: | 1)Laboratory of Veterinary Pathology, Faculty of Applied Biological Sciences, Gifu University, 1–1 Yanagido, Gifu 501-1193, Japan;2)Comparative Cancer Center, Faculty of Applied Biological Sciences, Gifu University, 1–1 Yanagido, Gifu 501-1193, Japan |
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Abstract: | A 5-year-old male ferret presented with an enlarged canalicular testis in the left inguinal region. Microscopically, the enlarged testis consisted of a diffuse intimately admixed proliferation of c-kit-positive germ cell-like and Wilms tumor-1 protein-positive Sertoli cell-like components, but no Call-Exner body was detected. In addition, the compact proliferation of steroidogenic acute regulatory protein-intense positive interstitial cells was identified in a separate peripheral area of the mass. Based on histopathological and immunohistochemical findings, the tumor was diagnosed as a mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor. |
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Keywords: | ferret immunohistochemistry interstitial cell tumor mixed germ cell-sex cord-stromal tumor testis |
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