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Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret
Authors:Saki INOUE  Kayoko YONEMARU  Tokuma YANAI  Hiroki SAKAI
Affiliation:1)Laboratory of Veterinary Pathology, Faculty of Applied Biological Sciences, Gifu University, 1–1 Yanagido, Gifu 501-1193, Japan;2)Comparative Cancer Center, Faculty of Applied Biological Sciences, Gifu University, 1–1 Yanagido, Gifu 501-1193, Japan
Abstract:A 5-year-old male ferret presented with an enlarged canalicular testis in the left inguinal region. Microscopically, the enlarged testis consisted of a diffuse intimately admixed proliferation of c-kit-positive germ cell-like and Wilms tumor-1 protein-positive Sertoli cell-like components, but no Call-Exner body was detected. In addition, the compact proliferation of steroidogenic acute regulatory protein-intense positive interstitial cells was identified in a separate peripheral area of the mass. Based on histopathological and immunohistochemical findings, the tumor was diagnosed as a mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor.
Keywords:ferret   immunohistochemistry   interstitial cell tumor   mixed germ cell-sex cord-stromal tumor   testis
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