Light-addressable potentiometric sensor for biochemical systems |
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| Authors: | D G Hafeman J W Parce H M McConnell |
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| Institution: | Molecular Devices Corporation, Palo Alto, CA 94304. |
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| Abstract: | Numerous biochemical reactions can be measured potentiometrically through changes in pH, redox potential, or transmembrane potential. An alternating photocurrent through an electrolyte-insulator-semiconductor interface provides a highly sensitive means to measure such potential changes. A spatially selectable photoresponse permits the determination of a multiplicity of chemical events with a single semiconductor device. |
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