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Pseudoalteromone B: A Novel 15C Compound from a Marine Bacterium Pseudoalteromonas sp. CGH2XX
Authors:Yu-Hsin Chen  Jimmy Kuo  Jui-Hsin Su  Tsong-Long Hwang  Yung-Husan Chen  Chia-Hung Lee  Ching-Feng Weng  Ping-Jyun Sung
Affiliation:Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan; Email: kb5634@yahoo.com.tw (Y.-H.C.); chlee016@mail.ndhu.edu.tw (C.-H.L.).
Abstract:A novel 15C compound, pseudoalteromone B (1), possessing a novel carbon skeleton, was obtained from a marine bacterium Pseudoalteromonas sp. CGH2XX. This bacterium was originally isolated from a cultured-type octocoral Lobophytum crassum, that was growing in cultivating tanks equipped with a flow-through sea water system. The structure of 1 was established by spectroscopic methods. Pseudoalteromone B (1) displayed a modestly inhibitory effect on the release of elastase by human neutrophils.
Keywords:pseudoalteromone   Pseudoalteromonas   anti-inflammatory   Lobophytum crassum   elastase
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