Enhanced protein adsorption at the solid-solution interface: dependence on surface charge

By the use of infrared internal reflection spectroelectrochemistry, it has been possible to observe an enhanced adsorption of porcine fibrinogen onto a germanium surface at potentials more positive than -200 millivolts relative to a saturated calomel electrode. The enhanced adsorption was observed directly at the interface between the solid and the aqueous solution.