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Regulation Effects and Mchanism of Amino Acids on Lipid Metabolism in Mammals
Authors:XIAO Kai-li  YIN Yu-long  ZHANG Lin  DENG Bai-chuan  DENG Jin-ping  TAN Cheng-quan
Institution:1. College of Animal Science, South China Agricultural University, Guangzhou 510642, China; 2. Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China
Abstract:Lipid metabolism not only affects human health but also is vital to livestock and poultry production. Therefore, it is necessary to study the nutrition regulation strategy of lipid metabolism. This paper mainly introduces the four amino acids which are important for the regulation of lipid metabolism, including methionine (Met),leucine (Leu),arginine (Arg) and glutamate (Glu), and summarizes the regulation effects and mechanism on lipid metabolism of the four amino acids at the physiological level, cellular level and molecular level. This paper introduces these four amino acids in the role of nutritional research, physiological effects in animal experiments,the mechanism of regulation effect on lipid metabolism and the combination effect. Meanwhile,the regulation and mechanism of amino acid on lipid metabolism in adipose,liver and muscle tissue were emphatically discussed. This paper reviews the progress of four amino acids in basic research and livestock production application, and further analyze the potential directions in the future research on the deep mechanism of lipid metabolism to clarify the regulation effects and potential mechanism of the amino acids on mammals' lipid metabolism, which was aimed to provide a reference for the accuracy using of amino acids.
Keywords:amino acids  mammals  lipid metabolism  regulation  mechanism  
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