Research Advances on Calf Pathogenic Diarrhea and Vaccine

Calf diarrhea is a kind of digestive tract disease caused by a variety of pathogenies, which has a great impact on the survival, growth and development of calves. Escherichia coli, bovine rotavirus, bovine coronavirus and other pathogens often cause diarrhea in calves, in addition, the secondary infection and mixed infection also occurre in different pathogens, which lead to great difficulty for prevention of calf diarrhea. A variety of vaccines have been developed for the prevention and treatment of calf diarrhea at home and abroad. Now, except only minor commercial calf diarrhea vaccines have been found in abroad, there is no one multivalent commercial calf diarrhea vaccine in China. Based on previous study, the progress of pathogens and vaccines for calf diarrhea were elaborated in the study, which could provide exploitation references for the commercial calf diarrhea vaccine in China.