Cold agglutinin disease in a cat

A case of cold agglutinin disease associated with trauma and exposure to lead is described in a domestic cat. A definitive diagnosis was made on the basis of autohaemagglutination at cold temperatures and histopathology. Exposure to lead has been associated with cold agglutinin disease in other species. The cat spontaneously recovered after removal of the lead from its body. Cold agglutinin disease has been reported twice in the cat.