Rigidin E,a New Pyrrolopyrimidine Alkaloid from a Papua New Guinea Tunicate Eudistoma Species |
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| Authors: | Rohan A Davis Lane V Christensen Adam D Richardson Rosana Moreira da Rocha Chris M Ireland |
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| Institution: | 1.Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA;2.Universidade Federal do Paraná, Departamento de Zoologia, C.P. 19020, 81.531-980, Curitiba, Brazil |
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| Abstract: | A new pyrrolopyrimidine alkaloid, rigidin E (1) and the known metabolites rigidin (2) and 1-methylherbipoline (3) have been isolated from a Papua New Guinea tunicate Eudistoma sp. A combination of spectroscopic data were used to determine the structures of these metabolites. |
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| Keywords: | Tunicate Eudistoma sp rigidin E cytotoxicity HCT 116 A431 |
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