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| 银杏叶提取物对体外培养心肌膜微血管内皮细胞分泌NO和ET-1的影响 | |
| 引用本文： | 田启超,张涛,胡格,田丽芳,穆祥,刘长松. 银杏叶提取物对体外培养心肌膜微血管内皮细胞分泌NO和ET-1的影响[J]. 中国农学通报, 2007, 23(11): 4-7 |
| 作者姓名： | 田启超 张涛 胡格 田丽芳 穆祥 刘长松 |
| 作者单位： | 1. 四川农业大学动物科技学院,雅安,625014;河北沧州职业技术学院,沧州,061001 2. 中国农业大学动物医学院,北京,100094 3. 北京农学院北京市兽医学(中医药)重点实验室,北京,102206 4. 四川农业大学动物科技学院,雅安,625014 |
| 基金项目： | 北京市自然科学基金;北京市教委学术创新团队 |
| 摘 要： | 研究银杏叶提取物(EGb761)对微血管内皮细胞分泌NO和ET-1的影响。采用体外培养大鼠心肌膜微血管内皮细胞(RMMMVECs)模型,测定其一氧化氮(硝酸还原酶法)和内皮素-1(ELISA法)分泌量的变化。EGb761能显著性提高RMMMVECsNO和ET-1的分泌量,且NO/ET-1值没有显著性变化。 |
| 关 键 词： | 银杏叶提取物 大鼠 心肌膜微血管内皮细胞 内皮素-1 |
| 修稿时间： | 2007-05-11 |
Effect of NO and ET-1 on the Myocardial Membrane Microvascular Cells in vitro by EGb761 |
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| Tian Qichao,Zhang Tao,Hu Ge,Tian Lifang,Mu Xiang,Liu Changsong. Effect of NO and ET-1 on the Myocardial Membrane Microvascular Cells in vitro by EGb761[J]. Chinese Agricultural Science Bulletin, 2007, 23(11): 4-7 | |
| Authors: | Tian Qichao Zhang Tao Hu Ge Tian Lifang Mu Xiang Liu Changsong |
| Affiliation: | 1College of Animal Science and Technology, Sichuan Agricultural College, Yaan 625014; 2College of Veterinary Medicine, China Agricultural University, Beijing 100094; ~Depanment of Animal Science and Technology, Beijing A gricultural College, Beijing 102206; 4Cangzhou Vocational college of Technology, Cangzhou 061001 |
| Abstract: | To study the influence of EGb761 on the secretion of NO and ET-1 in microvascular endothelial cells.Using the model of rat myocardium microvascular endothelial cells(RMMMVECs)in vitro,the secretions of NO by the means of nitrate reductase and ET-1 by the means of ELISA were determined.EGb761 could enhance the secretion of NO and ET-1 in RMMMVECs,and the ratio of NO and ET-1 was hardly changed. |
| Keywords: | NO |
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