| 北陆花青素的抗氧化作用 |
| |
| 引用本文： | 王荣姣,李昭华,黄红林,陈少云,董先智. 北陆花青素的抗氧化作用[J]. 安徽农业科学, 2011, 39(12): 7061-7063 |
| |
| 作者姓名： | 王荣姣 李昭华 黄红林 陈少云 董先智 |
| |
| 作者单位： | 王荣姣(南华大学药物药理研究所,湖南衡阳,421001;中国科学院生物物理研究所,北京,100101);李昭华,董先智(中国科学院生物物理研究所,北京,100101);黄红林(南华大学药物药理研究所,湖南衡阳,421001);陈少云(晨星越橘科技发展有限公司,辽宁丹东,118000) |
| |
| 基金项目： | 国家星火计划，中国科学院研发实验服务基地测试基金 |
| |
| 摘 要： | [目的]探讨北陆花青素的抗氧化作用。[方法]分别采用Fenton反应体系、邻苯三酚自氧化体系、亚油酸体系和普鲁士蓝法来测定北陆花青素对OH.和O2-.的清除作用、对脂质过氧化物的抑制作用及其还原能力进行评价,并以维生素C和葡萄籽花青素作为阳性对照。[结果]北陆花青素的抗氧化能力高于葡萄籽花青素和维生素C,对OH.和O2-.具有很强的清除作用,其IC50分别为0.345mg/ml和34.28μg/ml,对脂质过氧化物有明显的抑制作用并有较高的还原能力。[结论]北陆花青素是一种潜在的具有抗氧化活性的天然药物。
|
| 关 键 词： | 北陆（Northland） 花青素 自由基 抗氧化 |
Antioxidative Activity of Anthocyanins from Northland |
| |
| WANG Rong-jiao et al. Antioxidative Activity of Anthocyanins from Northland[J]. Journal of Anhui Agricultural Sciences, 2011, 39(12): 7061-7063 |
| |
| Authors: | WANG Rong-jiao et al |
| |
| Affiliation: | WANG Rong-jiao et al(Institute of Pharmacy and Pharmacology,University of South China,Hengyang,Hunan 421001) |
| |
| Abstract: | [Objective] To explore antioxidative activity of anthocyanins from Northland.[Method] Using anthocyanins from grape seeds and vitamin C as positive control,Fenton reacting system,pyrogallol autoxidation system,linoleic acid system and Prussian blue method were respectively employed to determine OH· scavenging activity,O2-·scavenging activity,inhibitive effect on lipid peroxidation and reducing capacity of anthocyanins from Northland.[Result] Antioxidative activity of anthocyanins from Northland was higher than that in anthocyanins from grape seeds and vitamin C.Anthocyanins from Northland had strong scavenging activities on OH· and O2-·,IC50 of which was 0.345 mg/ml and 34.28 μg/ml,respectively.Furthermore,it was also provided with obvious inhibiting activity on lipid peroxidation and reducing capacity.[Conclusion] Anthocyanins from Northland may be a potential natural medicine with antioxidative activity. |
| |
| Keywords: | Northland Anthocyanins Free radical Antioxidation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
