Effect of azadirachtin-derived decalin (perhydronaphthalene) and dihydrofuranacetal (furo[2, 3-fo]pyran) fragments on the feeding behaviour of Spodoptera littoralis |
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| Authors: | Wally M. Blaney Monique S. J. Simmonds Steven V. Ley James C. Anderson Stephen C. Smith Anthony Wood |
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| Affiliation: | 1. Behavioural Entomology Group, Department of Biology, Birkbeck College, London, WC1E 7HX, UK;2. Behavioural Entomology Group, Biological Interactions Section, The Jodrell Laboratory, Royal Botanic Gardens, Kew, Richmond, Surrey, TW9 3AB, UK;3. University Chemical Laboratory, Lensfield Road, Cambridge, CB2 1EW, UK;4. Department of Chemistry, Imperial College of Science, Technology and Medicine. London SW7 2AY, UK |
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| Abstract: | Decalin and dihydrofuranacetal fragments related to those in azadirachtin exhibited antifeedant activity against larvae of the African leaf-worm Spodoptera littoralis. Boisd. All the decalin fragments tested were methoxy (C11) derivatives of azadirachtin. The most active decalin fragment had a ketone substitution at C7. Overall, the compounds were more active when tested in combinations of one decalin fragment and one dihydrofuranacetal fragment than when tested singly. Although some of these combinations did show significant levels of antifeedant activity, sometimes coupled with a synergistic effect, they were not as active as either azadirachtin or dihydroazadirachtin. |
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