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Bone biomarkers and risk of fracture in two‐ and three‐year‐old Thoroughbreds
Authors:B F JACKSON  P K DYSON  C LONNELL  K L P VERHEYEN  D U PFEIFFER  J S PRICE
Institution:1. Department of Veterinary Clinical Sciences, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK;2. Clevedale Veterinary Practice, Upleatham, Redcar, TS11 8AG, UK;3. C. Lonnell: Department of Clinical Science, Swedish University of Agricultural Sciences, Uppsala, Sweden;4. Department of Veterinary Basic Sciences, The Royal Veterinary College, Royal College Street, London NW1 0TU, UK
Abstract:The aim of this study was to determine whether bone biomarkers (osteocalcin, PICP, ICTP and CTX‐I) could be used to identify 2‐ and 3‐year‐olds at increased risk of fracture in the subsequent flat racing season. It was concluded that these bone biomarkers cannot be used to identify 2‐ and 3‐year‐olds that sustain a fracture. Whether bone biomarkers have better predictive value in older horses or when measured serially in the same animal remains to be determined.
Keywords:horse  Thoroughbred  biomarker  fracture  training  bone
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