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高良姜提取物的降血糖活性
引用本文:王辉,;翟红莉,;梅文莉,;易博,;蔡彩虹,;曾艳波,;董文化,;戴好富.高良姜提取物的降血糖活性[J].热带生物学报,2014(2):179-181.
作者姓名:王辉  ;翟红莉  ;梅文莉  ;易博  ;蔡彩虹  ;曾艳波  ;董文化  ;戴好富
作者单位:[1]中国热带农业科学院热带生物技术研究所/农业部热带作物生物学与遗传资源利用重点实验室/海南省黎药资源天然产物研究与利用重点实验室,海南海口571101; [2]中国人民解放军第一八七医院,海南海口571159
基金项目:海南省重大科技专项(ZDZX2013008-4);海南省中药现代化专项资金(2011ZY002,2012ZY008)
摘    要:利用α-葡萄糖苷酶抑制活性筛选对海南产高良姜的不同提取部位及其主要化学成分进行降血糖活性测试。结果表明,高良姜的根茎、花、果实和茎叶的乙醇提取物及其主要成分高良姜素、山奈素、异鼠李素和槲皮素对α-葡萄糖苷酶的抑制活性显著高于阳性对照药阿卡波糖。

关 键 词:高良姜  提取物  降血糖活性  α-葡萄糖苷酶

Hypoglycemic Activity of Extract of Alpinia officinarum
Institution:WANG Hui,ZHAI Hongli,MEI Wenli,YI Bo,CAI Caihong,ZENG Yanbo,DONG Wenhua(Institute of Tropical Bioscience and Biotechnology / Ministry of Agriculture Key Laboratory of Biology and Genetic Resources of Tropical Crops / Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, CATAS, Haikou 571101, China;Department of Pharmacy, the 187th hospital of PLA, Haikou 571159, China)
Abstract:Hypoglycemic activity of main constituents and extracts of different parts of the plant lesser galangal (Alpinia officinarum Hance) were determined using inhibitory assay of α-glucosidase.The results indicated that ethanol extracts of the rhizome,flowers,fruits and leaves of A.officinarum and its main ingredients galangin,kaempferol,isorhamnetin and quercetin all produced obviously higher inhibitory activities against α-glucosidase than the positive control acarbose.Hypoglycemic activities of flowers,fruits and leaves of A.officinarum were first reported,which provides basis for the study and development of the waste material in the harvest of A.officinarum.
Keywords:Alpinia officinarum  hypoglycemic activity  α-glucosidase
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