犬细粒棘球绦虫的驱虫试验

为了进一步做好包虫病防控工作，开展了犬细粒棘球虫驱虫试验，以观察吡喹酮片对犬细粒棘球绦虫的驱除效果。选择当地土种犬作为试验犬，分为试验组和对照组，按5 mg/kg剂量分别直接投喂试验药品和对照药品，连续进行三次投药，试验投药前后对犬粪便分别采取犬细粒棘球绦虫抗原检测；同时在犬投药前后，分别采取羊粪便进行细粒棘球绦虫抗原检测。试验组和对照组的驱虫效果均为100%，但对照组犬的主动吞食率较低为0.38%，而试验组犬主动吞食率达到89.22%；在犬驱虫试验区域，羊只的细粒棘球绦虫感染率也大幅度下降，其中试验组感染率下降到了10%；对照组下降到23.33%。试验药品中加入天然成分掩盖吡喹酮的苦味，使犬的主动吞食率增高，且该药品相对松软有助于分割使用。因此该试验药品是比较理想的抗寄生虫药物，用于驱除犬细粒棘球绦虫效果较好，推荐剂量为5 mg/kg。

Deworming test of Echinococcus Granulosus in Dogs

In order to further improve the prevention and control of hydatid disease, this study carried out a deworming test against Echinococcus granulosus in dogs to observe the deworming effect of praziquantel tablets on Echinococcus granulosus in dogs. We selected local indigenous dogs as experimental dogs and divided them into experimental groups and control groups. We directly fed the test drug and control drug at a dose of 5 mg/kg, and administered the drugs three times in a row. The canine feces were tested for Echinococcus granulosus antigen before and after drug administration. At the same time, sheep feces were collected for Echinococcus granulosus antigen detection before and after the dogs were dosed. The deworming effect of both the test group and the control group was 100%, but the active ingestion rate of dogs in the control group was as low as 0.38%, while the active ingestion rate of dogs in the test group reached 89.22%. In the canine deworming test area, the infection rate of Echinococcus granulosus tapeworms in sheep also dropped significantly, with the infection rate in the test group dropping to 10%. The control group dropped to 23.33%. Natural ingredients are added to the test drug to mask the bitter taste of praziquantel, which increases the dog''s active swallowing rate. The drug is relatively soft and facilitates split use. Therefore, this experimental drug is an ideal anti parasitic drug and has a good effect in expelling Echinococcus granulosus in dogs. The recommended dose is 5mg/kg.