Screening study for potential lead compounds for natural product-based fungicides: I. Synthesis and in vitro evaluation of coumarins against Botrytis cinerea |
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| Authors: | Daoubi Mourad Durán-Patrón Rosa Hmamouchi Mohamed Hernández-Galán Rosario Benharref Ahmed Collado Isidro G |
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| Institution: | Laboratoire de Chimie des Substances Naturelles et Hétérocycles, Université Cadi Ayyad, Faculté des Sciences Semlalia, BP 2390, Marrakech, Marocco. |
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| Abstract: | An efficient, one-pot synthesis of angular and linear dihydropyranocoumarins, along with C-6 and C-8 prenylated coumarins is reported. These compounds, together with single- and furanocoumarins, were tested for their potential antifungal activity against the phytopathogen Botrytis cinerea Pers ex Fr. The results show that furanocoumarins may be able to control the fungus B cinerea. |
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| Keywords: | crop‐protection agents antifungal activity Botrytis cinerea coumarins |
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