| 铜绿假单胞菌呼吸机相关肺炎的临床特点与防治对策 |
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| 引用本文： | 吴斌,郭兰萍,陈衡华.铜绿假单胞菌呼吸机相关肺炎的临床特点与防治对策[J].湛江医学院学报,2002,20(5):348-348,354. |
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| 作者姓名： | 吴斌 郭兰萍 陈衡华 |
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| 作者单位： | 广东医学院呼吸疾病研究所 广东湛江524001
(吴斌，郭兰萍)，广东医学院呼吸疾病研究所 广东湛江524001(陈衡华) |
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| 摘 要： | 目的：探讨铜绿假单胞菌(PA)呼吸机相关肺炎(VAP)的临床特点与防治对策。方法：对36例由PA所致VAP的患者进行回顾性分析。结果：PA—VAP的临床特点与其它肺炎相似，但病情较重，并发症多，易发生多器官功能衰竭(MSOF)．病死率高。PA对多种抗生素产生耐药，而对泰能、舒普深、头孢他啶仍有较高的敏感性。治疗好转率52．8％，病死率41．7％。结论：PA耐药菌株多，合理使用抗生素及加强各环节的严格消毒，对PA—VAP的防治十分有益。
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| 关 键 词： | 铜绿假单胞菌 呼吸机相关肺炎 临床特点 防治 |
| 文章编号： | 1005-4057(2002)-05-0348-02 |
Clinical characteristics of ventilator-associated pneumonia due to Pseudomonas aeruginosa and its prophylactic-therapeutic measures |
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| WU Bin,GUO .Lan ping,CHEN Heng hua.Clinical characteristics of ventilator-associated pneumonia due to Pseudomonas aeruginosa and its prophylactic-therapeutic measures[J].Journal of Guangdong Medical College,2002,20(5):348-348,354. |
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| Authors: | WU Bin GUO Lan ping CHEN Heng hua |
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| Abstract: | Objective:To summarize the clinical characteristics of ventilator associated pneumonia due to Pseudomonas aeruginosa (PA VAP)and its prophylactic therapeutic measures.Methods:The clinical data of 36 patients with PA VAP were retrospectively analyzed.Results: Compared with pneumonia caused by other bacteria,patients with PA VAP were more serious condition,more complications easier to develop multiple system organ failure (MSOF)and higher mortality.Although P.aeruginosa was resistant to many antibiotics,it was sensitive to Tienam,Sulperazon and ceftazidime.The effective rate and mortality in the present study were 52.8% and 41.7%,respectively.Conclusion:Antibiotic resistance in P.aeruginosa is wide.The use of appropriate antibiotics and strictly sterilizing measures may be immensely beneficial for the prophylaxis and treatment of PA VAP. |
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| Keywords: | Pseudomonas aeruginosa ventilator associated pneumonia respiratory infections |
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