An anti-inflammatory and immunomodulatory polysaccharide from Orbignya phalerata |
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Authors: | Bernadete Pereira da Silva Jos Paz Parente |
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Institution: | Bernadete Pereira da Silva,José Paz Parente, |
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Abstract: | A polysaccharide, a glucan with mean Mr of 1.0×106 (MP1), was isolated from the mesocarp of fruits of Orbignya phalerata. Chemical and spectroscopic studies indicated that MP1 has a highly branched glucan type structure composed of α-(1→4) linked
-glucopyranose residues with (3→4), (4→6), and with (3→6) branching points. MP1 enhanced phagocytosis in vivo and exhibited anti-inflammatory activity. |
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Keywords: | Orbignya phalerata Polysaccharides Anti-inflammatory activity Immunomodulatory activity |
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