Olfactory neuroblastoma in a horse |
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Authors: | Yamate Jyoji Izawa Takeshi Ogata Keiko Kobayashi Osamu Okajima Ryoko Kuwamura Mitsuru Kotani Takao Aoki Mika |
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Affiliation: | Department of Veterinary Pathology, Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan. |
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Abstract: | An 11-year-old thoroughbred gelding was euthanatized because of right nasal cavity tumor. The tumor consisted of round to oval cells with a scanty cytoplasm and hyperchromatic nuclei. Homer-Wright rosettes and pseudorosettes, as well as microcysts were seen. Neoplastic cells were immunoreactive to vimentin, S-100 protein, and neuron-specific enolase, glial fibrillary acidic protein and microtube-associated protein in varying degrees, indicating neurogenic nature. Based on these findings, this tumor was diagnosed as an olfactory neuroblastoma. Since this type is an uncommon tumor showing histological variety, the nature is discussed. |
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