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Influence of age on bronchoscopic findings in healthy beagle dogs
Authors:E Mercier  M Bolognin  AC Hoffmann  C Tual  MJ Day  C Clercx
Institution:1. Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, University of Liège, Boulevard de Colonster 20(B44), 4000 Liège, Belgium;2. Division of Veterinary Pathology, Infection and Immunity, School of Clinical Veterinary Science, University of Bristol, Langford BS40 5DU, United Kingdom;1. Brown University/Rhode Island Hospital, Providence, Rhode Island, U.S.A.;2. DePuy Mitek (a Johnson & Johnson Company), Raynham, Massachusetts, U.S.A.;1. Cardiology Service, Faculty of Veterinary Sciences, National University of La Plata (FVS-NULP), La Plata, Argentina;2. Laboratory of Reproductive Physiology, FVS-NULP, La Plata, Argentina;3. National Research Council (CONICET), La Plata, Argentina;4. Radiology Service, FVS-NULP, La Plata, Argentina;5. Ultrasonography Service, FVS-NULP, La Plata, Argentina;1. Physical Medicine Institute, Physiotherapy Department, School of Health Sciences, Medical University of Silesia, Poland;2. Physiotherapy Institute, Physiotherapy Department, School of Health Sciences, Medical University of Silesia, Poland;3. Rehabilitation Institute, Physiotherapy Department, School of Health Sciences, Medical University of Silesia, Poland
Abstract:The aims of this study were to evaluate the effect of age on bronchoscopic features and bronchoalveolar lavage fluid (BALF) cellularity in dogs. Thirty healthy beagle dogs from three age groups were included: young dogs (10 months to 4.5 years of age; n = 8), middle-aged dogs (5–8 years old; n = 13) and older dogs (>8 years; n = 9). Haematology, thoracic radiography, bronchoscopy and bronchoalveolar lavage were performed; bronchoscopic findings were scored and BALF total and differential cell counts were determined. The total bronchoscopic score was higher in older dogs; these dogs had more irregular bronchial mucosa, more prominent mucosal vessels and bronchiectasis. Younger dogs had a higher percentage of neutrophils in BALF compared with middle-aged and old dogs and a higher percentage of lymphocytes in BALF compared with middle-aged dogs. The results show that age has an effect on bronchoscopic features of airways and the composition of BALF in the dog.
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