Recent advances in the epidemiology,diagnosis and control of diseases caused by porcine circovirus type 2 |
| |
| Authors: | Llorenç Grau-Roma Lorenzo Fraile Joaquim Segalés |
| |
| Institution: | 1. Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Campus de la Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain;2. Departament de Sanitat i Anatomia Animals, Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, Barcelona, Spain;3. Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Barcelona, Spain;1. Sección Virología, Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay;2. División Sanidad Animal, Ministerio de Ganadería, Agricultura y Pesca, Constituyente 1476, Montevideo 11200, Uruguay;1. The Roslin Institute and The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, UK;2. Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA;3. Department of Biomedical Sciences and Pathobiology, Center for Molecular Medicine and Infectious Diseases, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA;1. University of Padua, Padua, Italy;2. The Pirbright Institute, Pirbright, Woking, UK;3. Department of Preventive Veterinary Medicine and Animal Health, College of Veterinary Medicine, University of São Paulo, São Paulo, SP, Brazil;;4. Empresa Brasileira de Pesquisa Agropecuária – Embrapa Pantanal, Corumbá, MS, Brazil;5. Laboratório de Ixodologia, Faculdade de Medicina Veterinária, Universidade Federal de Uberlândia, MG, Brazil;6. Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Campus de la Universitat Autònoma de Barcelona, Departament de Sanitat i d’Anatomia Animals, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain |
| |
| Abstract: | Post-weaning multisystemic wasting syndrome (PMWS) emerged as a significant disease affecting pig production in the 1990s although the causal agent, porcine circovirus type 2 (PCV2), and the disease itself, had existed in swine for many years prior to this. The important multifactorial ‘triggers’ of PMWS include the immune and infection status of the sow, the timing of PCV2 infection, variations in the virulence of PCV2, co-infections, immune modulation as well as host genetics and management factors. In terms of diagnosis, histopathological examination and the detection of PCV2 within lymphoid tissue remains the ‘gold standard’ as quantitative PCR techniques are currently not specific or sensitive enough. The recent commercial availability of PCV2 vaccines provides an excellent tool for reducing the impact of PMWS and other porcine circovirus-related diseases. This review assesses recent advances in the epidemiology, diagnosis and control of PMWS. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
