Successful long term treatment of a dog with psychomotor seizures using carbamazepine |
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Authors: | CT HOLLAND |
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Institution: | Department of Veterinary Anatomy, University of Sydney, New South Wales. |
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Abstract: | Psychomotor seizures (temporal lobe epilepsy) were diagnosed in a dog based on history, clinical findings and electroencephalography. Long-term seizure control was achieved with carbamazepine, despite serum drug concentrations which were low to unmeasurable. It is suggested that serum levels of carbamazepine are not a useful guide to clinical efficacy in the dog, that an unmeasured metabolite of carbamazepine may account for the anti-convulsant activity and that carbamazepine may be potentially useful in treating certain canine seizure disorders. |
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