Effects of Four Preparations of 0.05% Chlorhexidine Diacetate on Wound Healing in Dogs |
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| Authors: | SCOTT LOZIER DVM MS ERIC POPE DVM MS Dipiomate ACVS JOHN BERG DVM PhD |
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| Institution: | Department of Veterinary Medicine and Surgery, University of Missouri-Columbia. |
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| Abstract: | Four chlorhexidine diacetate (CHD) antiseptic wound lavage preparations were evaluated in vivo to determine their effects on second intention wound healing in the dog in vitro to determine their relative antibacterial activity against Staphylococcus intermedius. Chlorhexidine was diluted to 0.05% in sterile water, 0.9% sodium chloride, lactated Ringers solution (LRS), and LRS that was allowed to form a precipitate with CHD. Control solutions included sterile water and LRS. There were no significant differences in wound contraction or epithelialization. All 0.05% CHD preparations provided 100% bacterial kill. |
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