Phylogenetic analysis for the Seoul National University (Minnesota) miniature pig by mitochondrial DNA sequence polymorphism |
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| Authors: | Su‐Cheong YEOM Dae‐Young KONG Chung‐Gyu PARK Byeong‐Chun LEE Wang‐Jae LEE |
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| Institution: | 1. Center for Animal Resource Development, Bio‐max Institute,;2. Department of Theriogenology and Biotechnology, College of Veterinary Medicine,;3. Xenotransplantation Research Center, Seoul National University Hospital, Seoul, Korea;4. Department of Microbiology and Immunology, College of Medicine, Cancer Research Center,;5. Department of Anatomy, College of Medicine, Seoul National University, and |
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| Abstract: | Seoul National University (SNU) miniature pigs are originated from the Minnesota miniature pig. This study was conducted to investigate the maternal origin of SNU (Minnesota) miniature pigs and their phylogenetic relationships by analyzing the mitochondrial DNA (mtDNA) D‐loop (control region) sequence. Two mtDNA D‐loop sequences of the SNU miniature pigs were identified. On an unweighted pair‐group method with an arithmetic mean (UPGMA) phylogenetic tree analysis, the large white was the pig breed closest to the SNU miniature pig, and the pairwise distance analysis showed the same result. While mtDNA sequences of 4 pig breeds which were used to establish Minnesota miniature pig were not known, our result might be different from the history of the Minnesota miniature pig development. In conclusion, we thought that some haplotypes of the Minnesota miniature pig maternally were originated from the Large white pig, or that wild pigs had similar mtDNA sequences to the Large white pig, and all SNU miniature pigs were derived from this colony. |
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| Keywords: | mtDNA phylogeny SNU miniature pig |
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