Oral immunization of sows: anti-K88 antibodies in serum and milk of the sow and in serum of the piglets |
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| Authors: | Kortbeek-Jacobs N van Houten M |
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| Institution: | Departments of Immunology resp Bacteriology, Faculty of Veterinary Medicine, State University Utrecht, the Netherlands. |
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| Abstract: | Pregnant sows were immunized by oral application of live E. coli. The effect of immunization was demonstrated by measuring the titers of anti-K88 antibodies in sow serum, colostrum and milk as well as in piglet sera using enzyme-linked immunosorbent assays. The isotype involved in anti-K88 reactivity was found to be IgA. By comparing IgA-titers in colostrum and milk, the local production of this Ig-class in the mammary gland is suggested. |
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