Three new phenolic compounds from the roots of Glycyrrhiza yunnanensis |
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| Institution: | 1. Department of Biochemistry, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, VT 05405-0068, USA;2. Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655-0002, USA;3. Mayo Clinic, 200 First Street SW, Rochester, MN 55905-0001, USA |
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| Abstract: | Three new phenolic compounds (1–3), together with 16 known compounds (4–19), were isolated from the roots of Glycyrrhiza yunnanensis Cheng f. et L. K. Dai. On the basis of 1D and 2D NMR, HR-ESI-MS, and circular dichroism (CD) spectroscopic analysis, structures of the new compounds were elucidated as 2-(2′-methoxy-4′-hydroxy)-aryl-3-methy-6-hydroxy-benzofuran (1), (2S)-6,7-(2,2-dimethyldihydropyrano)-8-prenyl-4′-hydroxyflavanone (2), and 6-prenyl-7,3′,4′-trihydroxyflavone (3). Compounds 1, 3, 5, 12, 14, 15 and 16 showed antioxidant activity by an ABTS-based assay. |
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