Isolation of new flavan-3-ol and lignan glucoside from Loropetalum chinense and their antimicrobial activities |
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| Affiliation: | 1. Membres du CCAFU-OGE (Comité de cancérologie de l’Association française d’urologie – sous-comité Organes génitaux externes et rétropéritoine);2. Membres experts du CCAFU-OGE (Comité de cancérologie de l’Association française d’urologie – sous-comité Organes génitaux externes et rétropéritoine);1. School of Basic Sciences, Indian Institute of Technology Mandi, Kamand Campus, Mandi, HP 175005, India;2. Institute of Biophysics and Centre of Biomolecular Drug Research (BMWZ), Leibniz Universität Hannover, Herrenhäuser Strasse 2, 30419 Hannover, Germany;3. Institute of Technical Chemistry and Centre of Biomolecular Drug Research (BMWZ), Leibniz Universität Hannover, Callinstrasse 5, 30167 Hannover, Germany;4. Institute of Organic Chemistry and Centre of Biomolecular Drug Research (BMWZ), Leibniz Universität Hannover, Schneiderberg 1B, 30167 Hannover, Germany;5. School of Chemical Sciences, National Institute of Science Education and Research Bhubaneswar, Jatni Campus, Kurdha, Odisha, 752050, India;1. Bio-IT Fusion Technology Research Institute, Pusan National University, Busan, Korea;2. Department of Nanomaterials Engineering, Pusan National University, Busan, Korea |
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| Abstract: | Phytochemical and antimicrobial activity study on the ethanol extract of the leaves and stems of Loropetalum chinense led to the isolation of a new flavan-3-ol compounds, 8-[1-(3,4-dihydroxyphenyl)-3-methoxy-3-oxopropyl]-catechin (loropetaliside A) (1) and a new lignan glucoside, 1-(5-hydroxy-3-methoxyphenyl)-2-(2-β-glucopyranosyl-4-hydroxy-5-(1-(E)propen-3-ol)-phenyl)-propane-3-ol (loropetaliside B) (3) and several known compounds manglieside D (2), quercetin (4), kaempferol-3-O-D-glucopyranoside (5), quercetin-3-O-β-L-rhamnoside (6) and tiliroside (7). Their structures were elucidated on the basis of extensive spectroscopic analysis. |
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