Three new phenolic compounds from the leaves of Rosa sericea |
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| Institution: | 1. Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, People''s Republic of China;2. Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People’s Republic of China;1. Department of Biochemistry, Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal;2. Department of Neurology, Chonbuk National University Medical School, Jeonju, Chonbuk, Republic of Korea;3. Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Chonbuk, Republic of Korea;1. University of Bucharest, Faculty of Geology and Geophysics, Doctoral School of Geology, 6 Traian Vuia St., 020956 Bucharest, Romania;2. Hungarian Natural History Museum, Botanical Department, POBox 137, H-1431 Budapest, Hungary;3. Southwest Petroleum University, School of Geosciences and Technology, 8, Xindu Ave., Chengdu 610000, China;4. University of Bucharest, Faculty of Geology and Geophysics, Department of Geology, Laboratory of Palaeontology, 1, N. B?lcescu Ave., 010041 Bucharest, Romania |
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| Abstract: | Two new flavonoids, quercetin-3-O-β-d-xylopyranosyl-(1 → 2)-α-d-ribopyranoside (1) and kaempferol-3-O-β-d-xylopyranosyl-(1 → 2)-α-d-ribopyranoside (2), and one new phenolic derivative, gallicin-p-O-(6′-O-caffeoyl)-β-d-glucoside (3), together with twelve known compounds were isolated from the leaves of Rosa sericea (Rosaceae family). The structures of the new compounds were established by means of spectroscopic analysis including one- and two-dimensional NMR spectroscopy. Some of the isolated compounds were tested for the cytotoxicity of a breast cancer cell (MCF-7) line. The results showed that rubanthrone A (4) has moderate cytotoxicity against the MCF-7 cell line. |
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