Saponins from Glycine max Merrill (soybean) |
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| Institution: | 1. National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, MS 38677, USA;2. Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, MS 38677, USA;1. Department of Chemical Engineering, Ben-Gurion University of the Negev, Beer-Sheva, Israel;2. Department of Biomedical Engineering, Ben-Gurion University of the Negev, Beer-Sheva, Israel;3. Department of Computer science, Ben-Gurion University of the Negev, Beer-Sheva, Israel;4. Department of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel;5. Departments of Obstetrics and Gynecology, Hillel Yaffe Medical Center, Hadera, Israel |
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| Abstract: | Saponins are a diverse group of plant secondary metabolites with a wide array of activities, as well as a significant role in nutrition and health. Saponins occur as multi-component mixtures of compounds with very similar polarities. Soysaponins are a special group of saponins. These represent the main source of saponins in Glycine max (soybeans, Fabaceae). In a study of the chemical profiling of plants, to investigate the possible misidentification and authentication of dietary supplements, the hydro-alcoholic extract of G. max was investigated. Three new saponins, designated as soysaponins M1 (1), M2 (2) and M3 (3) along with seven known soysaponins (4–10) were isolated by normal and reverse phase liquid chromatography. All compounds were characterized by spectroscopic techniques including 2D NMR spectroscopy. |
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