| Changes of the liver metabolome following an intravenous lipopolysaccharide injection in Holstein cows supplemented with dietary carnitineOA |
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| 引用本文： | Wei Xu,Sandra Grindler,ákos Kenéz,Sven D?nicke,Jana Frahm,Korinna Huber.Changes of the liver metabolome following an intravenous lipopolysaccharide injection in Holstein cows supplemented with dietary carnitineOA[J].畜牧与生物技术杂志(英文版),2023(1):188-199. |
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| 作者姓名： | Wei Xu Sandra Grindler ákos Kenéz Sven D?nicke Jana Frahm Korinna Huber |
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| 作者单位： | 1. Beijing Research Center of Intelligent Equipment for Agriculture;3. Institute of Animal Science, Faculty of Agricultural Sciences, University of Hohenheim;4. Department of Infectious Diseases and Public Health, City University of Hong Kong |
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| 摘 要： | Background: Carnitine facilitates the flux of long-chain fatty acids for hepatic mitochondrial beta-oxidation, which acts to ameliorate the negative energy balance commonly affecting high-yielding dairy cows. Inflammation triggered by lipopolysaccharide(LPS) load can however pose a challenge to the metabolic integrity via the expression of pro-inflammatory mediators, leading to immune system activation and respective metabolic alterations. The effect of enhanced carnitine availability on hepatic...
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